Natural history data in neurodegenerative disease for clinical studies design

 
   Lead Investigator:    Herve Rhinn
   Institution      :    Alector
   E-Mail           :    herve.rhinn@alector.com
   Proposal ID      :    1615



   Proposal Description:
   Our goal is to use the clinical assessment and biomarker data to understand how  best to design proof-of-concept studies in AD, FTD and other neurodegenerative  conditions. This will serve the purpose of more quickly bringing therapeutics  to patient care practice.  Composite endpoints and novel statistical analysis methods will be explored in  the hopes of increasing the ability of detecting meaningful treatment effects  in proof-of-concept studies.